ImmPort gene list example

Draft

Interested in immunology biological processes and the genes involved in pathways?

ImmPort is a subset of immunology-related pathways from reactome.org

Home page at https://www.immport.org/home

Select Shared data > Gene lists

In search box, search ontology, e.g., “Burst” for respiratory burst

immport01

results, three sets, which we can collect genes from. For example, click on Negative regulation …

immport02

Column Symbol contains the list of genes. This pathway contained only five genes, so simple enough just to copy those five for further use. Displayes, ImmPort provies a way to download a text file (.txt), which will be a comma separated version of the displayed table which can be imported into your spreadsheet app.

Once you have extracted the list of genes for the three processes related to respiratory burst, you may wish to produce a Venn Diagram, like the one displayed below, or bring the tables into Cytoscape.

Venn diagram of ImmPort results